'A lucid, lively study of a complex subject' Sydney Morning Herald 'I'm obsessed with this book' Dr Rangan Chatterjee 'Too important to ignore' Jeremy VineA radical new approach to depression from the publishers who brought you Michael Mosley's international bestsellers Worldwide, depression will be the single biggest cause of disability in the next 20 years. But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still . . . until now. In this game-changing book, world neuroscience expert Professor Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycle of stress, inflammation and depression.The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into the story of Western medicine, how we have got it wrong as well as right in the past, and how we could start getting to grips with depression and other mental disorders much more effectively in the future. 'An important book, a hopeful book, for anyone who wants to think about depression in a new way.' Tom Insel MD, Co-founder and President, Mindstrong Health UK 'Edward Bullmore has led us out of the dark ages and shone a light on the crucial link between systemic inflammation and mental illness. This book … heralds a new field of personalised psychiatry in the same way that we are seeing personalised therapy in cancer.' Sir Robert Lechler, President, Academy of Medical Sciences (UK)